Technology Selection And Process Design

Technology Selection and Process Design

Technology Selection and Process Design 

Technology Evaluation Methodology
Multi-Criteria Decision Analysis – A systematic evaluation framework considering:
• Technical Performance: Process efficiency, yield, and quality output
• Economic Viability: Capital investment, operating costs, and ROI
• Regulatory Acceptance: Established regulatory precedent and approval timelines
• Supplier Capability: Vendor experience, support, and financial stability
• Implementation Risk: Technical complexity and project execution risk

Pilot Scale and Process Development
• Technology demonstration and proof-of-concept studies
• Process optimization and parameter determination
• Scale-up risk assessment and mitigation strategies
• Technology transfer planning and execution
• Intellectual property considerations and licensing agreements

Equipment Selection Strategy
Single-Use vs. Stainless Steel Systems

Single-Use Technology Benefits:
• Reduced cross-contamination risk
• Simplified cleaning and validation
• Faster changeover between products
• Lower initial capital investment
• Reduced utility requirements

Stainless Steel System Advantages:
• Long-term cost effectiveness for high-volume production
• Robust and proven technology platform
• Easier process control and monitoring
• Better suited for continuous manufacturing
• Higher capacity and throughput capabilities

Automation and Control Philosophy
• Level of Automation: Manual, semi-automatic, or fully automated operations
• Control System Architecture: DCS, PLC, or hybrid control strategies
• Data Management: Historians, MES integration, and data analytics
• Cybersecurity: Industrial control system security frameworks
• Operator Interface: HMI design and operator training requirements